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& Gerich, J

Pineal peptides do not have the extensive clinical trial data that pharmaceutical sleep aids do

It acts from a lack of equilibrium between two neurotransmitters in the basal ganglia: dopamine (inhibitory) and acetylcholine (excitatory)

Injection site reactions: Minor local irritation, redness, or pain at SubQ injection sites typically transient

Thrombin peptide (TP508) promotes fracture repair by up-regulating inflammatory mediators, early growth factors, and increasing angiogenesis

297,307 In addition, astrocytes lose AQP4 channels in their endfeet and down-regulate expression of glutamate transporters, thus adding to excitotoxic damage of oligodendrocytes